The pursuit of understanding the molecular architecture of biological macromolecules has been a cornerstone of modern structural biology. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and electron microscopy (EM) have emerged as indispensable tools in this domain. Each method comes with distinct advantages and limitations, making their selection...
Exosomes, small vesicles released by cells, play an increasingly prominent role in intercellular communication and disease modulation. These nano-sized particles contain a diverse array of molecular cargo, including proteins, lipids, RNA, and metabolites, which serve as biomarkers for a variety of physiological conditions. Exosome lipidomics and metabolomics are key fields that focus on...
Liposomes have emerged as a promising tool in the field of drug delivery, offering a means to encapsulate therapeutic agents and target their release to specific sites within the body. This approach, known as liposome localization, leverages the unique properties of liposomes to enhance the efficacy and reduce the side effects of various treatments. In this article, we will delve into...
RNA (ribonucleic acid) plays a crucial role in the central dogma of molecular biology, serving as an intermediary between DNA and proteins. Beyond its traditional role in protein synthesis, RNA has emerged as a key player in regulating gene expression through various mechanisms. The function and regulation of RNA are intimately tied to its structure, making RNA structure analysis a vibrant...
Introduction
Microcrystal Electron Diffraction (MicroED) is a cutting-edge technique that has revolutionized the field of structural biology. By harnessing the power of electron microscopy, MicroED allows scientists to determine the atomic structure of nanoscale crystals. This article explores the principles behind MicroED, its applications, and its potential impact on various...
Creative Biostructure, a leading provider of structural biology services, announces its comprehensive suite of bacterial extracellular vesicle (BEV) services. These services empower researchers to harness the full potential of BEVs for advanced therapeutic and diagnostic applications.
BEVs are nanosized vesicles derived from bacteria that play a crucial role in intercellular...
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