RNA Splicing and How to Target It
What Is RNA Splicing?
RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions (exons) and non-coding regions (introns). RNA splicing removes the introns from the pre-mRNA molecule and joins together the exons to form a mature mRNA molecule that can be translated into protein.
What Is the Process of RNA Splicing?
The process of splicing is carried...
Principle, Advantages, Protocol, and Applications of RNA CLIP-Seq
Introduction to CLIP Sequencing
RNA binding protein (RBP) is a key protein that regulates gene expression at the post-transcriptional level. RBP forms ribonucleoprotein complexes by binding to transcribed RNA. The complex can control RNA biogenesis, stability, cellular localization, and transport, as well as RNA molecules' fate and function. As a result, understanding post-transcriptional regulation in various biological processes requires a high-resolution and accurate protein-RNA...
ChIP-Based Phosphorylation Detection: A Powerful Tool for Unraveling Cellular Signaling
Cellular signal transduction pathways are complex networks that allow cells to respond to their environment, with phosphorylation playing a central role in these processes. The ability to detect phosphorylation in a genetic level is crucial for understanding how these pathways function in both healthy and diseased states. Chromatin immunoprecipitation (ChIP) has emerged as a powerful technique for the analysis of protein-DNA interactions, including the study of phosphorylation...
Profacgen Launches Single Molecule Array Testing Service for Protein Analysis Research
Profacgen, a leading provider of protein research services, today announced the launch of its Single Molecule Array (SiMoA) testing service. This highly sensitive technology enables researchers to detect ultra-low abundance proteins with unparalleled accuracy, opening up new possibilities for biomarker discovery and disease research.
SiMoA is a revolutionary technology that brings protein detection into the era of single-molecule analysis. By coating tiny magnetic beads with hundreds...
RNAi-Mediated Gene Silencing in Plants: Mechanisms and Applications
Introduction
The discovery of RNA interference (RNAi) has revolutionized the field of plant biology, providing a powerful tool for functional genomics and crop improvement through targeted RNAi gene silencing. RNAi is a natural process by which cells regulate the expression of specific genes. By harnessing this process, scientists can selectively silence genes in plants, allowing for the study of gene function and the development of crops with desirable traits.
The Mechanism of...
Lifeasible Provides Customized Solutions for Plant Protection
Lifeasible, a leading provider of scientific research and development services, is offering customized solutions for plant protection through its cutting-edge research capabilities, crop pest and weed information, pesticide R&D strategies, plant protection technologies, data analysis, and software development.
In an era where food security and biodiversity are increasingly threatened by climate change, pests, and diseases, the protection of plants has never been more critical. Plants are...
Matexcel Introduced Cytocompatibility Test Service for Research Use
Matexcel, a leading provider of advanced biocompatibility testing solutions, announces the launch of its cytocompatibility test service. This in vitro testing service is designed to assess the biocompatibility of various materials and extracts, providing crucial insights for medical device and material researchers.
Cytocompatibility, the ability of a material to demonstrate a suitable host response in a specific application, is a critical factor in the development and approval of...
Ensuring Biocompatibility: A Guide to Cytocompatibility Testing
What is Cytocompatibility?
Before we dive into the testing process, it's essential to understand what cytocompatibility means. Cytocompatibility refers to the ability of a material, such as those used in medical devices, to interact with cells in a way that is non-toxic and biocompatible. In other words, a cytocompatible material will not cause an adverse reaction when it comes into contact with the body's tissues and cells.
Why is Cytocompatibility Testing Important?...
Promising Technologies to Uncover the Mechanism behind Aging
As human beings grow older, our bodies undergo a series of changes that ultimately lead to the aging process. From wrinkles and gray hair to decreased energy levels and increased susceptibility to diseases, aging is a complex phenomenon that scientists have been studying for decades. One crucial aspect of aging research company is understanding the underlying mechanisms that drive the aging process.
Over the past years, many scientific technologies such as telomere biology, multi-omics...
The Best Glycolic Acid Creams in Pakistan: Achieve Radiant Skin
Glycolic acid, a powerhouse ingredient in the realm of skincare, has garnered significant attention for its ability to exfoliate the skin effectively, revealing a brighter and more youthful complexion. As a member of the alpha-hydroxy acid (AHA) family, glycolic acid works by breaking down the bonds between dead skin cells, promoting their shedding and paving the way for new skin to surface. With the increasing awareness of its benefits, many brands now offer glycolic acid creams tailored for...
Immune System Tissue Microarrays for Research Usage
CD BioSciences, a US-based biotechnology company focusing on the development of imaging technologies, is excited to announce the launch of its new Immune System Tissue Microarrays for the scientific community to study the complex interactions of the immune system in various tissues. These innovative products offer researchers a powerful tool to unravel the complexities of the immune system and accelerate the development of new therapies.
Tissue microarray is a recent innovation in the field...
Accelerated Aging Testing Services for Medical Devices
STEMart, a US-based provider of comprehensive services for all phases of medical device development, has announced the launch of its new Accelerated Aging Testing Services for medical device manufacturers to ensure the long-term reliability and safety of their products.
The Accelerated Aging Testing utilizes high temperatures for a period of time to simulate the effects of real-time aging, artificially accelerating the aging process. This test allows manufacturers to bring products to market...
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